Enzyme Production Leader

DNA Script in a nutshell
DNA Script is a leading company in manufacturing de novo synthetic nucleic acids using an enzymatic technology. The company aims at accelerating innovation in life science and technology through rapid, affordable, and high-quality DNA synthesis. DNA Script's approach leverages nature's billions of years of evolution in synthesizing DNA to set a new standard for how nucleic acids are made and accelerate the adoption of synthetic biology across diverse disciplines such as biopharma, sustainable chemistry and data storage.
To date, DNA Script has raised over 16 M€ of financing, mostly through equity funding brought by prestigious players such as Illumina Ventures, Merck Ventures, Sofinnova Partners, Kurma Partners and Idinvest. The company partners with leading institutions, in particular Institut Pasteur.

Position open at DNA Script
DNA Script is looking for an enzyme production leader in order to ensure the production of DNA Script proprietary enzymes: first for internal R&D use and in a latter stage for DNA production operation.
The assignment will involve first implementing new production process, managing internal production team, identifying and managing partnership for better enzyme expression system & scale-up.
You will be also responsible for the design, development and validation of enzyme production system and processes.

Opportunity and Challenges
We are looking to assemble a team of best-in-class, innovative and passionate people gathering their talents and skills to achieve one goal: bring to the world the next ultimate tool in biotechnology.
We offer the opportunity of joining a dynamic, international and highly skilled team of a high potential biotech startup. We have put in place competitive benefits (salary, equity, healthcare, meal voucher and public transportation) along with a unique opportunity to work in the heart of Paris

Experience and Skills

Must Have
Enzyme production and purification bioprocesses Bioprocess development for Bacteria Fermenter culture operations and development Enzyme purification operation and development Bioprocess scale-up QC methods for enzyme characterization Skills and ability to deliver complex and large quantity information into a synthetic and useful manner Attention to details Leadership skills Good organizational skills Insightful /results focused

Nice to have
Experience with different over-expression systems Experience with secretion systems Bioprocess development for Yeast Bioprocess development for mammalian cells Attraction to the start-up world
Holds a Master or PhD degree in the field of Biological Process Engineering, Chemical engineering, Biotechnology or similar.

Has +5 years of hands-on and industrial experience in protein production / purification and preferably upscaling of processes to industrial scale.